FGF21 是什么?
成纤维细胞生长因子21( fibroblast growth factor 21,FGF21) 属于成纤维细胞生长因子家族FGF19( fibroblast growth factor 19,FGF19) 的亚型,不具有促成纤维细胞生长活性,且不与肝素特异性结合,是一种调节机体代谢的分泌型蛋白。在骨骼肌、肾脏、心脏以及血管和脂肪组织中 fgf21 表达比肝脏中高约 7~10 倍。FGF21可靶向脑、心脏、骨骼肌以及肾脏和肠等多种组织器官发挥作用。
BioVendor 艾美捷 FGF21检测试剂盒针对成纤维细胞生长因子21的研究有着比较深刻和有意义的影响。
BioVendor 艾美捷FGF21(人)检测试剂盒标曲:
BioVendor 艾美捷 FGF21检测试剂盒已发表文章(部分):
Ahola S, Auranen M, Isohanni P, Niemisalo S, Urho N, Buzkova J, Velagapudi V, Lundbom N, Hakkarainen A, Muurinen T, Piiril? P, Pietil?inen KH, Suomalainen A.Modified Atkins diet induces subacute selective ragged-red-fiber lysis inmitochondrial myopathy patients. EMBO Mol Med. 2016 Nov 2;8(11):1234-1247.
Bisgaard A, S?rensen K, Johannsen TH, Helge JW, Andersson AM, Juul A.Significant gender difference in serum levels of fibroblast growth factor 21 inDanish children and adolescents. Int J Pediatr Endocrinol. 2014;2014(1):7.
BonDurant LD, Ameka M, Naber MC, Markan KR, Idiga SO, Acevedo MR, Walsh SA,Ornitz DM, Potthoff MJ. FGF21 Regulates metabolism Through Adipose-Dependent and -Independent Mechanisms. Cell metab. 2017 Apr 4;25(4):935-944.e4.
Bookout AL, de Groot MH, Owen BM, Lee S, Gautron L, Lawrence HL, Ding X,Elmquist JK, Takahashi JS, Mangelsdorf DJ, Kliewer SA. FGF21 regulates metabolismand circadian behavior by acting on the nervous system. Nat Med. 2013Sep;19(9):1147-52.